Molecular Assessment of Lymph Nodes in Patients With Resected (Stage I to IIIA) Non-Small Cell Lung Cancer

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Molecular Assessment of Lymph Nodes in Patients With Resected (Stage I to IIIA) Non-Small Cell Lung Cancer
This study is currently recruiting participants.
Verified by University Hospital, Strasbourg, France, January 2009
Sponsored by: University Hospital, Strasbourg, France

Information provided by: University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier: NCT00213733

Purpose
This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigators would like to analyse tumor tissue by allelotyping and comparing these results with those observed in the primary lung tumor to establish a cartography of molecular alteration in resected lung cancer. For non histopathologically positive lymph nodes, the investigators would like to research the presence (or not) of micrometastasis by allele-specific PCR (polymerase chain reaction).



Condition
Lung Cancer




MedlinePlus related topics: Cancer Lung Cancer
U.S. FDA Resources
Study Type: Observational
Study Design: Prospective
Official Title: Research of Molecular Markers for Diagnosis and/or Prognosis in Lymph Node Metastasis of Resected Non-Small Cell Lung Cancer


Further study details as provided by University Hospital, Strasbourg, France:


Estimated Enrollment: 150
Study Start Date: June 2004
Detailed Description:
Genetic: It is a prospective study during two years with three years for follow-up. No control group is recruited.

Eligibility


Genders Eligible for Study: Both
Accepts Healthy Volunteers: No

Criteria
Inclusion Criteria:

Patients with resectable non-small cell lung cancer (stage I to IIIA), with a complete resection of the tumor and paired lymph nodes.
Informed consent is required.
Exclusion Criteria:

Another cancer
Chemotherapy before surgical treatment
Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00213733


Contacts
Contact: Michèle BEAU-FALLER, MD 33.3.88.12.71.79 Michele.Faller@chru-strasbourg.fr


Locations
France
Service de Chirurgie Thoracique, Hôpital Civil Recruiting
STRASBOURG, France, 67091
Contact: Jean-Marie WILHM, MD jean-marie.wilhm@chru-strasbourg.fr
Sub-Investigator: Gilbert MASSARD, MD
Sub-Investigator: Xavier DUCROCQ, MD
Sub-Investigator: Jean-Marie WILHM, MD
Sub-Investigator: Mircea-Dan VASILESCU, MD
Service de Pneumologie, Hôpital Lyautey Recruiting
STRASBOURG, France, 67091
Contact: Elisabeth QUOIX, MD 33.3.88.11.63.02 Elisabeth.Quoix@chru-strasbourg.fr
Sub-Investigator: Elisabeth QUOIX, MD
Sub-Investigator: Bertrand Mennecier, MD
Service d'Anatomie Pathologique, Hôpital de Hautepierre Recruiting
STRASBOURG, France, 67098
Contact: Jean-Pierre BELLOCQ, MD 33.3.88.12.70.53 Jean-Pierre.Bellocq@chru-strasbourg.fr
Sub-Investigator: Jean-Pierre BELLOCQ, MD
Sub-Investigator: Agnès MECHINE, MD
Sub-Investigator: Bernard GASSER, MD
Service de Pneumologie, Hôpital de Hautepierre Recruiting
STRASBOURG, France, 67098
Contact: Romain KESSLER, MD 33.3.88.12.78.38 Romain.Kessler@chru-strasbourg.fr
Sub-Investigator: Romain KESSLER, MD
Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital de Hautepierre Recruiting
STRASBOURG, France, 67098
Contact: Michèle BEAU-FALLER, MD 33.3.88.12.71.79 Michele.Faller@chru-strasbourg.fr
Contact: Christine STEMMER
Sub-Investigator: Pierre OUDET, MD
Sub-Investigator: Marie-Pierre GAUB, MD

Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
Principal Investigator: Michèle BEAU-FALLER, MD Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital de Hautepierre

More Information

Responsible Party: University Hospital, Strasbourg, France ( Emmanuel LAVOUE, Directeur Adjoint de la DRCI )
Study ID Numbers: 3207
Study First Received: September 13, 2005
Last Updated: January 9, 2009
ClinicalTrials.gov Identifier: NCT00213733 [history]
Health Authority: France: Ministry of Health

Keywords provided by University Hospital, Strasbourg, France:
Lung cancer patients
non-small cell lung cancer
molecular marker
lymph node completed resected
Lung cancer samples and paired lymph node resected



Study placed in the following topic categories:
Thoracic Neoplasms
Non-small cell lung cancer
Respiratory Tract Diseases
Lung Neoplasms
Lung Diseases
Neoplasm Metastasis
Carcinoma, Non-Small-Cell Lung
Neoplasms, Glandular and Epithelial
Carcinoma



Additional relevant MeSH terms:
Neoplasms by Site
Respiratory Tract Neoplasms
Neoplasms
Neoplasms by Histologic Type



ClinicalTrials.gov processed this record on February 10, 2009


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